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These disruptions in fuel homeostasis are not clearly related to their primary action of fluid management, raising concerns for patients with metabolic syndrome, in which high blood pressure coexists with obesity, insulin resistance, glucose intolerance and dyslipidemia

Food categories that have traditionally leaned on indulgence, routine, or emotional association may find themselves on uncertain ground

Side effects may often be eased by adjusting the dose-escalation schedule, which a licensed healthcare provider can help with

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